SVF + ACP therapy is a modern highly effective method of treating joint diseases by injecting autologous stem cells into the joint cavity in combination with its own enriched blood plasma.
The method has shown high efficacy in the treatment of patients with osteoarthritis of the hip, knee and other joints, as well as local cartilage defects, and is actively used in orthopedic clinics worldwide. In some cases, SVF+ACP therapy can delay joint replacement by reducing pain and expanding the patient's functional capabilities.
The technique combines two methods that stimulate tissue regeneration at once – treatment with proprietary enriched blood plasma (ACP) and the use of proprietary stem cells derived from adipose tissue (SVF).
The body's cells have a unique ability to repair themselves. Stem cells can speed up recovery. Modern technologies make it possible to obtain stem cells from adipose tissue quickly and safely. The stem cells of adipose tissue contained in the stromal vascular fraction (SVF) are similar in their properties to stem cells originating from bone marrow. They are able to differentiate into cells of bone, fat, cartilage and muscle tissue and secrete a large number of cytokines and growth factors, which makes it possible to use their unique properties for joint repair.
Indications for the procedure
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Cartilage defects
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Osteoarthritis of the knee, ankle, hip joints
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Arthrosis of the hand joints
Main effects of SVF + ACP
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Reduction of local inflammation
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Reduction of pain syndrome
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Prevention of tissue fibrosis
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Anti-apoptotic effect (slowing down the process of cell death)
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Stimulation of tissue remodeling
When fatty tissue stem cells are enriched with autologous blood plasma, their positive properties are enhanced several times, which contributes to joint recovery.
How is the procedure performed?
The procedure begins with minimally invasive extraction of the patient's adipose tissue from the appropriate "donor" area (for example, abdomen, waist or hip), followed by centrifugation in special syringes to isolate the stromal vascular fraction (SVF). Next, SVF is mixed with the patient's activated blood plasma (ACP), obtained from whole blood also by centrifugation, and injected into the damaged joint.
The injection is performed under local anesthesia or intravenous sedation (optional). The procedure takes about 45 minutes.
Before the injection, the patient needs to schedule tests. If the patient plans to perform the manipulation under intravenous sedation, consultation with an anesthesiologist is also necessary.
Required analyses:
- General clinical blood test with calculation of leukocyte formula
- Antibodies to HIV 1/2 + p24 antigen
- Hepatitis B Virus Surface Antigen (HBsAg)
- Antibodies to hepatitis C virus (anti-HCV), IgG
- Determination of antibodies to Treponema pallidum
Treatment is carried out only as prescribed by an orthopedic traumatologist.
Prepared by specialists of the Sports Traumatology and Orthopedics clinic.
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