In 1983, she graduated from the Semashko Moscow Medical Dental Institute, specializing in medical practice.
1983-1986 - trained in clinical residency in psychiatry at the VNTSPZ of the USSR Academy of Medical Sciences.
1986-1989 – postgraduate studies in psychiatry at the VNTSPZ of the USSR Academy of Medical Sciences.
1989 - defended her PhD thesis in psychiatry.
1989-1990 — worked in The Research Institute of Clinical Psychiatry VNTSPZ of the USSR Academy of Medical Sciences was a junior researcher at the Department of Middle-aged psychoses.
1990-1991 — Acting Senior Researcher at the Department for the Development of Scientific Research on Mental Health Issues.
1991-1999 — worked as a senior researcher at the Department of Non—medicinal Methods of Treatment and Intensive Care of the Federal State Institution Moscow Research Institute of Psychiatry of the Ministry of Health of the Russian Federation,
1999 — 2013 — worked as a leading researcher, from 2013 to the present — as Head of the Department of Psychopharmacotherapy of the V. P. Serbsky National Research Medical Center of the Ministry of Health of the Russian Federation.
The main area of scientific research is the diagnosis and therapy of affective mood disorders. The department headed by Kostyukova E.G. conducts research aimed at developing medicinal methods of relief therapy and secondary prevention of relapses of affective mood disorders.
The results of the unit's work formed the basis for recommendations for practitioners on the treatment of affective mood disorders. He is the co-author of two federal clinical guidelines, ten monographs and two patents, and has more than 250 scientific publications, including in foreign publications.
He is a member of the Editorial board of the P.B. Gannushkin Journal of Psychopharmacotherapy, a member of the Expert council of the World Federation of Societies of Biological Psychiatry, a member of the problem commission of the Federal State Budgetary Institution National Medical Research Center of Psychiatry and Narcology of the Ministry of Health of the Russian Federation.
Throughout the entire period of scientific work, he carries out medical advisory, pedagogical and lecture activities within the framework of the training program for residents, educational seminars, advanced training courses for doctors and regional scientific and practical conferences. Participates in the organization of specialized symposiums at all-Russian conferences, makes presentations, presenting the scientific results of the work of the headed department.