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Pregnancy after IVF

pregnancy after ivf

Long preparation, lots of research, careful implementation of medical recommendations, IVF protocol and an exciting two weeks of waiting for the result after embryo transfer – finally, all this is left behind: pregnancy has arrived, as confirmed by the HCG test. Once again, the woman is overwhelmed by many questions and worries. What should I do next? How to behave while waiting for a baby? Is pregnancy after IVF different from a natural pregnancy? How will the birth go?

Features of pregnancy after IVF

By the end of the first trimester, hormone therapy, which was prescribed after embryo transfer, is canceled. The further course of pregnancy is no different from the one that naturally occurs. However, given that IVF protocol is used by women with a burdened medical history, monitoring of such pregnancies should be as thorough as possible, especially in the case of multiple pregnancies.

After confirming the fact of pregnancy, all patients undergo a series of mandatory examinations and tests. Many of them are performed by women even before the IVF protocol, but if necessary, the doctor can re-prescribe them

What tests and examinations are carried out

In the first trimester, consultations with an ophthalmologist, an otorhinolaryngologist, and an endocrinologist are necessary to diagnose a pathology that may affect the course of pregnancy.

During pregnancy, blood tests are performed to detect anemia and iron deficiency, and monthly urine tests are performed to exclude asymptomatic bacteriuria and proteinuria.

After a positive HCG result, the patient undergoes an ultrasound examination to confirm pregnancy. This is possible as early as 3 weeks after embryo transfer. It is usually performed by a reproductologist who led the ART program.

The study shows exactly where the embryo was implanted. Although embryo transfer into the uterine cavity is carried out under ultrasound control, in 1% of cases, due to uterine contractions, embryo implantation occurs in the fallopian tube.

It is mandatory to perform ultrasound and biochemical screening (b-hCG, RARP-A-test) to determine the risk of chromosomal abnormalities.

During pregnancy, it is necessary to perform 3 mandatory important ultrasound examinations in each trimester, but if necessary, the doctor may prescribe additional ones.

When is ultrasound performed

The first ultrasound screening is performed during pregnancy at 11-13 weeks. In the future, mandatory ultrasound examinations are performed on time:

  • 18-21 weeks
  • H0-34 weeks

Ultrasound screening in the first trimester

The first trimester ultrasound is performed during pregnancy from 11 weeks 0 days to 13 weeks +5 days.

At this time, it is already possible to assess the anatomy of the fetus and, most importantly, the presence of ultrasound markers of chromosomal abnormalities is determined, such as the thickness of the cervical fold in the fetus, the presence of a nasal bone. Then, based on the results of ultrasound parameters and biochemical blood parameters, the risk of chromosomal abnormalities in the baby is calculated.

Ultrasound screening in the second trimester (18-21 weeks) allows:

  • To detect malformations – at this time it is possible to visualize all the organs and structures of the fetus, as well as to assess its size.
  • To assess the condition of the placenta and the place of its attachment, exclude its complete presentation or marginal presentation (this may increase the risk of bleeding during pregnancy).
  • To assess the condition of the cervix, whether there are signs of isthmic-cervical insufficiency.

If the pregnancy after IVF is single and proceeds normally, a standard monthly follow-up with a gynecologist is sufficient. In case of multiple pregnancies, follow-up examinations in the second trimester take place more often, every 2-3 weeks.

Ultrasound in the third trimester (30-34 weeks) is aimed at:

  • Assessment of fetal development, determination of its position
  • Checking the compliance of the size and weight of the baby with the terms of pregnancy
  • Position and degree of maturity of the placenta

Dopplerography reveals blood flow disorders in the umbilical cord artery, the middle cerebral artery of the fetus and the uterine arteries of the mother.

In the third trimester, follow-up examinations with a gynecologist take place every 2 weeks during the normal course of pregnancy.

Childbirth after IVF: self-delivered or cesarean?

IVF is not an indication for a cesarean section. As a rule, these patients give birth on their own.

The method of delivery depends only on obstetric indications.

Advantages of pregnancy management after IVF in EMC

EMC is a multidisciplinary clinic where doctors of various specialties (reproductologists, obstetricians and gynecologists, endocrinologists, geneticists and others) work. If necessary, all necessary doctors are involved in pregnancy management.
  • Obstetricians and gynecologists carry out pregnancy and deliver babies of any complexity: after IVF, in patients with concomitant diseases, they deliver through the natural birth canal in pregnant women with a scar on the uterus, with pelvic presentation and with multiple pregnancies,
  • The specialists of the EMC clinic have worked and interned in the best clinics in the world: in Europe, the USA and Israel.
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    Questions and answers

    Lump in my breast
    I have noted the lump in my breast periodically appeared following breastfeeding my first child (as a result of plugged duct). I did an ultrasound, but it revealed nothing, as if everything was normal. I knead my breast periodically and feel pain at those moments. Now I am pregnant, due date is on 20th. What should I
    do?? When to examine my breasts, is it possible to perform the examination during pregnancy and lactation?
    ...more
    The "lump" in the breast cannot occur after feeding, even if it was the plugged duct. You should not "knead" the breasts. If there is a problem or even if you think it is – the breast should be examined. Pregnancy and breastfeeding are not contraindications for this. Under normal conditions for pregnant women we
    recommend a breast examination during 1 and 3 trimester (before childbirth). There are no contraindications for breast examination in your case. You are welcome at any convenient time for examination and advice on breastfeeding.
    ...more
    Benign disease
    I have a benign lump in one breast size of 12.0*9.9 mm. Puncture or a biopsy will be done next week. I was told by mammologist that surgery is needed. As far as I know, concerning the surgery, axillary lymph nodes are to be removed together with the tumor. I also know that in Europe lymph nodes are testes for
    specific markers and only affected ones should be removed; if lymph nodes are no affected, they are not to be dissected and the surgery is minimally invasive. So what is your approach? Does it make sense to do it or you have the same methods and the same equipment?
    ...more
    If histological examination of the sample reveals fibroadenoma of basic type or tissue hyperplasia without atypia, or nodular type fibrocystic condition of the breast tissue, the question of surgical treatment should not arise. If biopsy reveals giant fibroadenoma sectoral resection is indicated, i.e. mass excision
    within the healthy tissues and lymph nodes will be removed. In case of non- benign histological result, i.e. carcinoma is detected, subsequent immunohistochemical examination is required as well as a clinical oncologist and surgeon consultation; and the decision on complex treatment will be taken by case management team. With regard to the diagnosis and treatment methods in our center, each case is addressed individually. Sometimes we remove a benign area (for example, the area of hyperplasia with atypia) using the vacuum-needle technique through 3-4 mm incision. As for the surgical procedure protocols for benign breast tumors, benign simple fibroadenoma is not removed in America, Europe, Israel, etc. I would like to discuss your case with you in more details and perform some additional tests if needed, so I would be glad to see you at EMC’s Breast center.
    ...more
    Melanoma
    My mom had a mole (suspected for melanoma) removed in November 2015. Histology revealed lentigo melanoma in situ. We checked the slides back in the Netherlands, and the diagnosis was a superficial spreading melanoma of Clark 3 Т1а Beslow 0,8 stage; re-excision with capture of 1 cm of healthy skin is recommended. Is
    it possible to make re-excision and subsequent histology in your hospital? If so, how soon?
    ...more
    We absolutely agree with the opinion of the European colleagues: re-excision with a wider offset is required; according to the Russian Protocol it is necessary to move 2 cm from the peripheral edge. This is for counter insurance, as lentigo-melanoma is a favorable type, and previous surgery is likely to put an end to
    this story and the forecast is favorable. All the necessary manipulations for the study are possible in our Clinic; we have our own well-equipped laboratory with the possibility to ask the advice concerning the sample in Germany and Israel. You should make an appointment with the surgeon-oncologist (Marina Bissessar) in the nearest time to conduct the diagnostic re-excision. Hope to help!
    ...more
    A spot on the back and chest
    I have a spot on the back and chest, what could it be?
    A spot on the skin is one of the most common symptoms of various skin diseases. Infectious (viral, bacterial or fungal) as well as noninfectious skin including serious diseases and nevi (moles or birthmarks) can manifest as spots on the skin. You should go to the dermatologist for accurate diagnosis. The doctor will
    examine you and, if necessary, a special instrument (Dermatoscope, wood lamp) will be used. A skin scraping can also be done in the lesion for microscopy, cytology or culture. A treatment will be prescribed after diagnosis.
    ...more
    Batkaeva Nadezhda
    07 September 2016
    Uterine cancer
    My mom was diagnosed with the uterine cancer. She is 68 years of age and has an obesity of 4th grade (the growth of 166 cm, weight 135 kg) and hypertension. Admission to the radiology department was recommended. What should we do? As far as I know the surgery is the only method for cancer of the uterus to be removed.
    Is it really so that this surgery is only possible for young and relatively healthy persons?
    ...more
    It is not quite so. We can operate on any patient, but the issue is which complications can lead to patient’s death and which of them can just delay the recovery. From the anesthesiologist’s point of view, it is a major challenge to intubate patients with 4th degree obesity; the abdominal section is also possible,
    but there is a 100% risk of suture line disruption and inflammation, let alone the postoperative pneumonia, venous thrombosis, etc. There is another option such as vaginal hysterectomy which is more acceptable and relatively safe in obese patients. It is not a «treatment standard», however, as it allows not obtaining pelvic washings, but still there is a possibility of complete cure. Anesthesia remains a problem - both general and spinal. Radiation therapy without surgery is another acceptable treatment option besides vaginal hysterectomy. A chance of complete cure is still exists, but the survival rate is on average lower than in surgical treatment
    ...more
    Vladimir Nosov
    07 September 2016

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