In the EMC, choosing a drug for cancer treatment based on a genetic analysis of the tumor has become the norm. All types of molecular genetic tests are performed in the laboratory that can predict the effectiveness of therapy, help the doctor choose the drug necessary for a given patient and, by prescribing "targeted" (targeted) treatment, cure the patient, or, if the disease is already at a late stage, increase his life expectancy.
Cancer is often referred to as a "genome disease", thereby emphasizing that this disease is based on various genetic "breakdowns" of cells. Unfortunately, anyone can get cancer, and the genetic defects in the tumor will vary from person to person. This means that for successful cancer treatment, it is necessary to conduct a genetic analysis of cancer cells, as it is commonly said today, to study the molecular "portrait" of the tumor, since the personification of cancer treatment can significantly increase the effectiveness of the fight against this disease.
At the European Medical Center, choosing a drug for cancer treatment based on a genetic analysis of the tumor has become the norm. All types of molecular genetic tests are performed in the laboratory that can predict the effectiveness of therapy, help the doctor choose the drug necessary for a given patient and, by prescribing "targeted" (targeted) treatment, cure the patient, or, if the disease is already at a late stage, increase his life expectancy.
Targeted treatment differs favorably from chemotherapy in that it practically does not damage healthy cells and tissues of the body, affecting only a given "pathological" gene. This type of treatment is also very convenient because medications can be taken at home, as these medications are often available in tablet form.
For example, for the treatment of breast cancer, it is necessary to know whether sex hormone receptors are present in the tumor (analysis for the expression of estrogen and progesterone receptors). If the receptors are detected, the patient needs hormone therapy. In addition, a special HER2 receptor is detected in the tumor, which makes breast cancer sensitive to the drug herceptin, and such patients must necessarily be treated with this medication.
For the treatment of lung cancer, it is necessary to examine the tumor in our laboratory for EGFR, ALK receptors. These are small molecules that deliver intracellular signals that cause tumor cells to divide and grow rapidly. To block these receptors, we can use a whole arsenal of new drugs – afatinib, cetuximab, erlotinib, crizotinib, pemetrexed.
For the successful treatment of other types of tumors, such as intestinal cancer, head and neck tumors, stomach cancer, and melanoma, pathomorphologists at the EMC Histological Laboratory will also compile a molecular "portrait" of the tumor, which will help clinicians choose the only correct type of treatment for this patient.
Thus, the EMC implements an individual approach to treatment, which increases its effectiveness. The molecular portrait of a tumor in each patient is its own unique set of genes and their mutations.
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Questions and answers
Is there a better sleep aide i can get other than what I have been using over the counter
Is there a better sleep aide i can get other than what I have been using over the counter. I know getting Ambian is a big hassle but is here something in between? I've been using Ambian for about 10 years almost daily, if it matters.
Ambian is a one the brand names of Zolpidem. It's available in Russia. You can schedule appointment with neurologist (Dr. Maslak, for example) and doctor will do prescription for you ( for Zolpidem or maybe another sleeping pill).
Rhinoplasty after 40
I would like to do a rhinoplasty, but it is said in some sources that “rhino” is not indicated after 40.
Good afternoon, Lydia. Rhinoplasty is allowable in your age. Dr. Levine, for example, performs rejuvenation in conjunction with rhinoplasty. The human nose grows throughout life. It becomes longer and more unattractive in adulthood. The rhinoplasty in conjunction with a facelift helps to achieve more pronounced
results of rejuvenation.
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Levin Sergey
08 September 2016
What to do first
What should I do first: Laser Fraxel and then the fillers, or Vice versa?
Good afternoon, Larisa. It is usually recommended to start with laser rejuvenation techniques, and then "polish" the result with hyaluronic acid injections. We invite you for a consultation. You can make an appointment by tel.: + 7 (495) 933 -66-54
Karapetyan Marianna
08 September 2016
Malignant kidney tumor
CT scan revealed a malignant kidney tumor in my brother. The tumor size is 3x7, which corresponds to stage 2. Tell me, please, how long does it take for such a tumor to be developed? And is it possible to remove the tumor surgically (total kidney removal)?
For a more precise answer we need to assess patient’s CT scans ourselves. At the EMC’s Urology clinic, both total and partial kidney removal with tumor is performed using the da Vinci robot. These surgeries are very gentle with fast postoperative recovery.
Prostate cancer
I am 74 years old. Prostate cancer was diagnosed. Total PSA was 25.8 ng/ml. Outpatient check-up was carried out. Are "Zoladex" injections enough? Biopsy revealed moderately poorly-differentiated small-acinar prostate adenocarcinoma. Where to start?
You should start with an extended examination, namely: skeleton scintigraphy, pelvic MRI, oncological examination. If the results of these tests will be the normal: surgery or radiotherapy may be offered (both with/without “Zoladex” therapy). If the results are abnormal: radiation therapy with/without “Zoladex”
therapy or “Zoladex” therapy may be offered.
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