In the EMC, choosing a drug for cancer treatment based on a genetic analysis of the tumor has become the norm. All types of molecular genetic tests are performed in the laboratory that can predict the effectiveness of therapy, help the doctor choose the drug necessary for a given patient and, by prescribing "targeted" (targeted) treatment, cure the patient, or, if the disease is already at a late stage, increase his life expectancy.
Cancer is often referred to as a "genome disease", thereby emphasizing that this disease is based on various genetic "breakdowns" of cells. Unfortunately, anyone can get cancer, and the genetic defects in the tumor will vary from person to person. This means that for successful cancer treatment, it is necessary to conduct a genetic analysis of cancer cells, as it is commonly said today, to study the molecular "portrait" of the tumor, since the personification of cancer treatment can significantly increase the effectiveness of the fight against this disease.
At the European Medical Center, choosing a drug for cancer treatment based on a genetic analysis of the tumor has become the norm. All types of molecular genetic tests are performed in the laboratory that can predict the effectiveness of therapy, help the doctor choose the drug necessary for a given patient and, by prescribing "targeted" (targeted) treatment, cure the patient, or, if the disease is already at a late stage, increase his life expectancy.
Targeted treatment differs favorably from chemotherapy in that it practically does not damage healthy cells and tissues of the body, affecting only a given "pathological" gene. This type of treatment is also very convenient because medications can be taken at home, as these medications are often available in tablet form.
For example, for the treatment of breast cancer, it is necessary to know whether sex hormone receptors are present in the tumor (analysis for the expression of estrogen and progesterone receptors). If the receptors are detected, the patient needs hormone therapy. In addition, a special HER2 receptor is detected in the tumor, which makes breast cancer sensitive to the drug herceptin, and such patients must necessarily be treated with this medication.
For the treatment of lung cancer, it is necessary to examine the tumor in our laboratory for EGFR, ALK receptors. These are small molecules that deliver intracellular signals that cause tumor cells to divide and grow rapidly. To block these receptors, we can use a whole arsenal of new drugs – afatinib, cetuximab, erlotinib, crizotinib, pemetrexed.
For the successful treatment of other types of tumors, such as intestinal cancer, head and neck tumors, stomach cancer, and melanoma, pathomorphologists at the EMC Histological Laboratory will also compile a molecular "portrait" of the tumor, which will help clinicians choose the only correct type of treatment for this patient.
Thus, the EMC implements an individual approach to treatment, which increases its effectiveness. The molecular portrait of a tumor in each patient is its own unique set of genes and their mutations.
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Questions and answers
LASIK
Whether LASIK fits everyone?
The main age group for this operation are patients over 18 years with myopia, hyperopia and astigmatism. There are number contraindications for LASIC such as some chronic diseases, including eye diseases.
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Elias Raid
08 September 2016
Sudden rises of blood pressure
How to stabilize sudden rises of blood pressure, accompanied by nausea and vomiting in a patient with chronic hypertension (it is not always clear what comes first - nausea and vomiting and, as a consequence, the blood pressure increase, or Vice versa).
An adjustment of appropriate permanent antihypertensive therapy is required for blood pressure to be stabilized. It is best to schedule a consultation with the cardiologist and undergo heart ultrasound, 24-hour blood pressure monitoring and ECG. You can make an appointment by phone +7 (495) 933-66-55. Specialists of
the Cardiology Department will be happy to help you.
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Extrasystoles
Extrasystoles appeared on my husband’s ECG following smoking cessation. He has a serious intension to undergo a thorough examination. What kind on up-to-date methods are used in your clinic?
EMS offers the most up-to-date methods of examination for your husband to clarify the nature of arrhythmias. ECHO-cardiography, 24 hour Holter monitoring ECG, loading tests, and, if needed, 24-hour blood pressure monitoring as well as all laboratory tests are available at EMC’s cardiology department. There is an
option to undergo a comprehensive examination under the program "Health Status after 40", which includes specialists' consultations, diagnostic laboratory and instrumental tests. We will be happy to help you. You can make an appointment by phone +7 (495) 933-66-55.
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Dyagileva Mariya
08 September 2016
How soon another attempt is possible?
Twin pregnancy resulted from IVF, but cervical dilatation occurred and water broke at 20 weeks, so the pregnancy was not maintained. How soon another attempt is possible?
At least a year interval between childbirth and repeated IVF program is required. It is advisable to be prepared and to make every effort to get a singleton pregnancy.
Рolyp of the cervical canal
Hysteroscopy revealed a polyp of the cervical canal, it was removed, but there are plenty of micropolips. May I do IVF or they should be treated?
Usually, all polyps are removed at therapeutic and diagnostic hysteroscopy. It makes no sense to leave them in the uterus cavity. I think that if manipulation such as "Hysteroscopy with separate diagnostic curettage" was done, you have no polyps now and may safely prepare for IVF.
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