In the EMC, choosing a drug for cancer treatment based on a genetic analysis of the tumor has become the norm. All types of molecular genetic tests are performed in the laboratory that can predict the effectiveness of therapy, help the doctor choose the drug necessary for a given patient and, by prescribing "targeted" (targeted) treatment, cure the patient, or, if the disease is already at a late stage, increase his life expectancy.
Cancer is often referred to as a "genome disease", thereby emphasizing that this disease is based on various genetic "breakdowns" of cells. Unfortunately, anyone can get cancer, and the genetic defects in the tumor will vary from person to person. This means that for successful cancer treatment, it is necessary to conduct a genetic analysis of cancer cells, as it is commonly said today, to study the molecular "portrait" of the tumor, since the personification of cancer treatment can significantly increase the effectiveness of the fight against this disease.
At the European Medical Center, choosing a drug for cancer treatment based on a genetic analysis of the tumor has become the norm. All types of molecular genetic tests are performed in the laboratory that can predict the effectiveness of therapy, help the doctor choose the drug necessary for a given patient and, by prescribing "targeted" (targeted) treatment, cure the patient, or, if the disease is already at a late stage, increase his life expectancy.
Targeted treatment differs favorably from chemotherapy in that it practically does not damage healthy cells and tissues of the body, affecting only a given "pathological" gene. This type of treatment is also very convenient because medications can be taken at home, as these medications are often available in tablet form.
For example, for the treatment of breast cancer, it is necessary to know whether sex hormone receptors are present in the tumor (analysis for the expression of estrogen and progesterone receptors). If the receptors are detected, the patient needs hormone therapy. In addition, a special HER2 receptor is detected in the tumor, which makes breast cancer sensitive to the drug herceptin, and such patients must necessarily be treated with this medication.
For the treatment of lung cancer, it is necessary to examine the tumor in our laboratory for EGFR, ALK receptors. These are small molecules that deliver intracellular signals that cause tumor cells to divide and grow rapidly. To block these receptors, we can use a whole arsenal of new drugs – afatinib, cetuximab, erlotinib, crizotinib, pemetrexed.
For the successful treatment of other types of tumors, such as intestinal cancer, head and neck tumors, stomach cancer, and melanoma, pathomorphologists at the EMC Histological Laboratory will also compile a molecular "portrait" of the tumor, which will help clinicians choose the only correct type of treatment for this patient.
Thus, the EMC implements an individual approach to treatment, which increases its effectiveness. The molecular portrait of a tumor in each patient is its own unique set of genes and their mutations.
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Questions and answers
How to stop dreaming?
Can you tell me if there are any medications that stop a person dreaming? I have been dreaming constantly for a long time, and the dreams are always vivid and emotionally charged. I wake up tired, not wanting to do anything, and I feel only lethargy and apathy. I live in another city.
We have all the tools for an accurate, comprehensive diagnosis, and medical treatment of such conditions, as well as psychosocial rehabilitation, which is critical for returning to an active lifestyle. The support program includes modern methods of diagnosis, regular professorial meetings, and comprehensive
psychological and neurocognitive support. Unfortunately, all the necessary diagnostic and therapeutic interventions can only be done with the patient being present at the Clinic. We are ready to welcome you to the EMC. Inpatient and outpatient psychiatry clinics operate within the multidisciplinary hospital, which creates the most comfortable conditions for patients.
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Rivkina Natalya
09 November 2015
Baby teeth - treat or not?
Baby teeth do not need to be treated, because they will drop out in any case - is it true?
If the teeth are not cleaned properly white carious spots will appear underneath the soft plaque. This initial stage of decay is reversible: with proper hygiene the stain will gradually fade. The next stage is when the defect appears: the integrity of the enamel (the outer shell of the tooth ) is broken and a
cavity appears in the tooth . From this moment caries begins to develop more rapidly since the dentin (the hard tissue of the tooth located under the enamel) is less dense than enamel, and it becomes difficult to clean the teeth properly.
If microorganisms get into the cavity of the tooth where the nerve passes, this will cause pulpitis - inflammation of the pulp of the tooth (the pulp consists of blood vessels and nerves), which may be accompanied by pain, but in the milk teeth is usually asymptomatic.
Pain may occur later, when the nerve has died completely and infection occurs outside the tooth - in the bone. In addition to pain, pulpitis is sometimes accompanied by swelling of the gums, fistulas (channels between the foci of the infection and the gum) and loose teeth .
The pathological process - from the appearance of a white spot to the development of inflammation outside of the tooth root - can be fast and take a few months or last for years, depending on many factors.
To avoid problems with your child’s teeth , you should visit the paediatric dentist regularly. The first appointment with the dentist should be when the child is 1.5 years old. Following on from this there should be regular check-ups every 6 months, or more frequently as directed by the doctor.
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Diagnosed infertility - what to do?
I’m 27 years old, diagnosed infertility since 5 years ago, tubal factor and only one working ovary. Have gone through 3 tries of in vitro fertilization, one was stimulated, had no response, in all 3 cases I had only one oocyte. AMH 0,91. Do you think I have a chance for a pregnancy with my own oocyte? Sperm quality
is good.
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Yes, of course, you should fight for your oocytes. There is a variety of minimal stimulations: modified cycles, natural cycles etc. If these methods don’t work, so we will think about donor cells. But you must definitely give your ovaries a chance.
Severe cervical dysplasia
I have a transplanted kidney and I was recently found to have severe cervical dysplasia. The biopsy results are not yet back, but the physician says I must have my uterus and cervix removed. My question is: Can I have the operation in your clinic?
For severe cervical dysplasia, usually cervical conization is sufficient. If you have no plans for reproduction, or you already have children, then theoretically you can discuss having a laparoscopic removal of the uterus and cervix, but these decisions should not be made through correspondence. If you have a
referral for an operation in the city where you live, and have the opportunity to come to Moscow, come for a free consultation using "Second Opinion" promotion. If necessary, we can quickly provide operative treatment at a discount.
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Vladimir Nosov
09 November 2015
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